Actor Charlie Sheen's HIV treatment has successfully suppressed the virus.
The Hollywood wildman, 51, revealed he had the disease in November last year (15) and subsequently enrolled in a clinical trial of the revolutionary new drug PRO-140.
Charlie revealed in an interview that the drug has suppressed the virus to the extent that it is now practically undetectable in his bloodstream.
"It's impossibly amazing," the Hot Shots star told Daily Mail Online. "Personally, I think about how I felt on the day and how I feel today. Wow. Talk about a transformation. One minute you're on the road to perdition, the next you're on the road to providence. It's amazing."
Dr Nader Pourhassan, CytoDyn's Chief Executive Officer confirmed to Mail Online that the actor's last two blood tests had come back with the result 'Target Not Detectable', meaning the virus is completely suppressed.
Normally HIV is treated with a daily cocktail of drugs with the aim of ensuring that the virus does not take hold and cause acquired immune deficiency syndrome (AIDS).
However the new experimental drug, manufactured by U.S. medical company CytoDyn, only requires one injection per week. Although PRO-140 does not combat all strains of HIV, it is effective against R5, the strain which more than two thirds of HIV positive people are infected with, and if passed by medical experts for wider use could help treat millions.
"I thought for sure I'd be stuck on that cocktail forever, but look at me now," Charlie added. "I'm so grateful for the geniuses at CytoDyn for developing this and finding me."